Drug Development & Medical Science Laboratory

  • 徐雪瑩-1Drug Development & Medical Science Laboratory
  • Name: Hsue-Yin Hsu (徐雪瑩)
  •  Title: Professor
  •  Highest Degree: Ph.D of Medical Institute, Kaohsiung Medical University, Kaohsiung, Taiwan.
  •  Research expertise: Cancer Biology, Drug development, Radiation Biology
  •  E-mail:hsueyin@mail.tcu.edu.tw
  •  Office/ Laboratory Site: D830/D829
  •  Office/ Laboratory Tel.:038565301 #2610/2613
  •  Research Interests:
    1.New Anticancer Drug Development and Investigation for Therapeutic Combination.
    2.Evaluation of Cancer Resistance and Anti-angiogenesis in Cancer Therapy.
  • Recent Research Grants:

NO.

associated agency

Research Grant

period

1

Committee of Chinese Medicine and Pharmacy, Department of Health, Taiwan, R.O.C.

Effect of triptolide on cisplatin-induced growth inhibition and angiogenesis on tumor

2013/1/22~

2013/12/15

2

Committee of Chinese Medicine and Pharmacy, Department of Health, Taiwan, R.O.C.

Evaluation of radioprotection by combination of glycyrrhiza and tea polyphenols

2011/7/19~

2011/12/31

3

TOP INTERNATIONAL BIOMASS ENERGY CO.

Development and investigation of functional products derived from crops, Chinese herb medicines and Algae.

2009/10/1~

2010/9/30

4

Tzu Chi Foundation

Investigation of molecular mechanism on anti-tumor effect of Momordica charantia

2009/8/1~

2010/7/31

 

  • Recent Publications:

NO.

Title

Index

Publish Date

Journal

Author

1

Prolonged induction activates Cebpα independent adipogenesis in NIH/3T3 cells.

SCI

2013/1

PLoSOne

(2013: e51459)

Hsiao-Yun Shao,

Hsue-Yin Hsu,

Kuan-Sju Wu,

Siow-Wey Hee,

Lee-Ming Chuang,

Jih-I Yeh

2

Antimigratory Effects of theMethanol Extract fromMomordica charantia on Human Lung Adenocarcinoma CL1 Cells

SCI

2012/11

Evidence-Based Complementary and Alternative Medicine
(2012:p.819632~p.819643)

Hsue-Yin Hsu*,

Jung-Hsuan Lin,

Chia-Jung Li,

Shih-Fang Tsang,

Chun-Hao Tsai,

Jong-Ho Chyuan,

Shu-Jun Chiu,

Shuang-En Chuang*

3

Momordica charantia Extract Induces Apoptosis in Human Cancer Cells through Caspase- and Mitochondria-Dependent Pathways

SCI

2012/9

Evidence-Based Complementary and Alternative Medicine
(2012:p.261971~p.261981)

Chia-Jung Li,

Shih-Fang Tsang,

Chun-Hao Tsai,

Hsin-Yi Tsai,

Jong-Ho Chyuan,

Hsue-Yin Hsu*

4

Induction of Apoptosis by Ethanolic Extract of Corchorus olitorius Leaf in Human Hepatocellular Carcinoma (HepG2) Cells via a Mitochondria-Dependent Pathway

SCI

2012/8

Molecules
(17:p.9348~p.9360)

Chia-Jung Li,

Shang-Yu Huang,

Meng-Yu Wu,

Yu-Ching Chen,

Shih-Fang Tsang,

Jong-Ho Chyuan*

Hsue-Yin Hsu *

5

Quercetin 3-O-methyl ether protects FL83B cells from copper induced oxidative stress through the PI3K/Akt and MAPK/Erk pathway

SCI

2012/7

Toxicology and Applied Pharmacology
(264:p.104~p.113)

Hsiao-Ling Tseng,

Chia-Jung Li,

Lin-Huang Huang,

Chun-Yao Chen,

Chun-Hao Tsai,

Chun-Nan Lin*,

Hsue-Yin Hsu*

6

Synergistic anticancer activity of triptolide combined with cisplatin enhances apoptosis in gastric cancer in vitro and in vivo

SCI

2012/1

Cancer Letters
(319:p.203~p.213)

Chia-Jung Li,

Ching-Yu Chu,

Lin-Huang Huang,

 Ming-Hseng Wangb,

Lai-Fa Sheu,

Jih-I. Yeh*,

Hsue-Yin Hsu *

7

Kazinol Q from Broussonetia kazinoki Enhances Cell Death Induced by Cu(ll) through Increased Reactive Oxygen Species

SCI

2011/4

Molecules
(16:p.3212~p.3221)

Bai-Luh Wei,

Ying-Chieh Chen,

Hsue-Yin Hsu*

8

Widespread expression of prostate apoptosis response-4 (Par-4) in nasopharyngeal carcinoma.

SCI

2010/7

Head & Neck
(32.7:p.877~p.885)

Jeng-Woei Lee*,

Wei-Ting Hsiao,

Kuei-Fang Lee,

 Lai-Fa Sheu,

Hsue-Yin Hsu,

Lee-Ping Hsu,

Borcherng Su,

Moon-Sing Lee,

Yih-Chih Hsu,

Chung-Hsing Chang

9

Depletion of Securin Induces Senescence After Irradiation and Enhances Radiosensitivity in Human Cancer Cells Regardless of Functional p53 Expression

SCI

2010/6

International Journal of Radiation Oncology Biology and Physic
(77:p.566~p.574)

WEN-SHU CHEN,

YI-CHU YU,

 YI-JANG LEE,

JI-HSHIUNG CHEN,

HSUE-YIN HSU,

SHU-JUN CHIU*

10

Modulation of p53 by mitogen-activated protein kinase pathways and protein kinase C delta during avian reovirus S1133-induced apoptosis

SCI

2009/3

Virology
(385:p.323~p.334)

Ping-Yuan Lin,

Jeng-Woei Lee,

Ming-Huei Liao,

Hsue-Yin Hsu,

Shu-Jun Chiu,

Hung-Jen Liu,

Wen-Ling Shih*